From: Joachim (joachim@microdsi.net)
Date: 05/04/00-06:17:10 AM Z
You're right. All that means is that it's OK for your mice to chew
dichromate and still enjoy a meaningful sex life. Joachim
> -----Original Message-----
> From: Sarah Van Keuren [mailto:svk@steuber.com]
> Sent: Wednesday, May 03, 2000 12:15 PM
> To: Alt Photo
> Subject: Re: Dichromate Hazards
>
>
> As promised I'm getting back to Linda with info. from chemist Bradley J.
> Collins, Dept. of Health & Human Services, NIH sent to me March 2, 1999.
>
> Potassium Dichromate (Hexavalent): Reproductive Assessment by Continuous
> Breeding When Administered to BALB/c Mice in the Diet (CAS
> 7778-5--9) Study
> Number: RACB94014
> "Results of this study show that potassium dichromate is not a
> reproductive
> toxicant at concentrations up to 400ppm. The no-observable-adverse-effect
> level (NOAEL) was not established in this study as the 100ppmFl females
> displayed reduced MCV (? svk). A maximum tolerated dose (MTD) was reached
> for the 400 ppm FO and F1 animals based on slightly decreased
> body weights,
> increased feed consumption, and small decreases in MCV, MCH, and HGB (F1
> animals only)."
> There are two other reports: Study Number: RACVB95001 NTIS
> #PB97-12355 and
> RACB95002 NTIS #PB97-125363.
>
> All this is over my head and I could not find the reports on the website
> listed: http://157.9813.224/htdocs/RT-studies/RAC9401.htm etc.
> Looks as if
> one has to pay for the info. but my general impression is that rats can
> tolerate more than a molecule of chromium in their bodies without adverse
> effects.
>
> Sarah Van Keuren
>
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